Ginseng Root Extract 80% Ginsenosides

January 30, 2010 by Ginseng Reviews and Tips  
Filed under About Ginseng

Ginseng Root Extract 80% Ginsenosides

Product specification: 80% Ginsenosides(VU-VIS)

Latin name: Panax Genseng

Product type: Low Brown Powder

Part of the plant used: Root (Dried, 100% natural)

Extract method: Grain alcohol

What is Panax Ginseng Root extract?

   Panax ginseng root extract is from 4- 6year’s ginseng root after extraction, pesticide residue elimination,filtration and concentration.

   It has the advantage of preparative flexibility in the production of medicines,dietary supplements in some oral liquid medicine,capsule and cosmetics.ginseng root extract liquid with ginsenoside contents varying from 3% to 40%

   It is widely used in pharmaceutical,nutritional,health food and cosmetics industries.

Where will be Ginseng root Extract use to?

* Rg1 promote lymphocyte karyokinesis,promote,medulla cell synthesize

* Rg3 anti-cancer

* Rh1&Rg2 resume white blood cell and red blood cell

* Rb1 restrian centrum nerve system

* Rh2 restrain cancer cell proliferate

* Reexpand blood vessel

Packing Detail:

  Packed in paper-drums and two plastic-bags inside. Net weight:25kgs/drum.

Storage situation:

  Stored in a cool and dry well-closed container, keep away from moisture and strong light/heat.

Shelf life:

  Two years under well storage situation and stored away from direct sun light.

 

NUTRAMAX’s other leading Products

No.

Leading Products Specification:

1. Luo Han Guo Extract 80% Mrogosides

2. Blueberry P.E. 25% Anthocyanidins

3. Resveratrol  20%~99%

4. Flax Seed P.E. 20%~80% SDG

5. 98% 5-HTP

6. Green Tea Extract 95% Polyphenols

7. Rhodiola Rosae P.E. 3% Rosavins/1% Salidroside

8. Reishi Mushroom P.E. 30% Polysacchrides

9. Magnolia Bark P.E. 90% Honokiol+Magnolol

10. Red Clover P.E. 8%~40% Isoflavones

11. Kindey Bean Extract 1% Phaseolamin

12. Banaba Leaf P.E.  1%~20% Corosolic Acid

13. Epimedium Extract 10%~50% Icariin

14. Cinnamon Extract 20:1

15. Cassia Nomame P.E.  8%~60% Dimer Flavans

16. Gynostemma pentaphyllum P.E.85% Gypenoside

17. Sesamine  30%, 60%, 90% Sesamine

18. Grape Seed P.E.95% OPC

19. Pueraria (Kudzu Root) P. E. 40% Isoflavnis

20. Yohimbine P.E 8% Yohimbine

Contact information:

Company: Changsha Nutramax Inc.

FDA Registration Number: 15970949816

Add.:  F25,Jiahege BLDG, #217 Wanjiali Road,Changsha,China, 410016

Telephone:  86-731-2939655

Mobile: +86-13723886785

Fax number: 86-731-2938822

Thanks to nutramax for contributing this article to our Ginseng blog:

Changsha Nutramax Inc.–The leader supplier of Botanical Extracts/Herbal Extracts

Changsha Nutramax Inc., is one of the leading manufacturer of the Tea & Herbal Extracts in China, we do all for dedicated to the identification, development and production of natural active ingredients from Chinese herb, for use in the nutraceutical, pharmaceutical, health-food , functional beverage ,and cosmetics industries.

Have you claimed your Genesis site?

Related Blogs

  • Related Blogs on Cosmetics Industries
  • Related Blogs on Extract 1
  • Related Blogs on Flax Seed

Siberian Ginseng – Medicinal Uses, Interactions, Side Effects, Dosage

June 1, 2009 by Ginseng Reviews and Tips  
Filed under About Ginseng

Siberian Ginseng

Eleutherococcus senticosus (syn. Acanthopanax senticosus) is in the same botanic family as the Panax ginsengs (Araliaceae), but is not a member of the Panax genus and is therefore not considered a true ginseng. E. senticosus, also known as Eleuthero, is commonly referred to as Siberian or Russian ginseng because it is indigenous to Eastern Russia. The root or root bark is used medicinally.

Uses and Benefits:

Siberian ginseng is claimed to have powerful adaptogenic and tonic properties that can modulate stress and improve mental and physical performance under a wide variety of stressful conditions. It was discovered by Soviet researchers who were searching for an alternative to Asian ginseng and other adaptogenic herbs. Officially approved for use in Russia in 1962, Siberian ginseng became a popular commercial drink to help improve endurance. In traditional Chinese medicine, this plant is considered a minor tonic (named ci wu jia). It has been employed for bronchitis, digestion, heart ailments, rheumatism, headaches, and insomnia, and to generally restore vigor and health.

Pharmacology:

The eleutherosides (A-G) are considered the most important constituents in the roots of Siberian ginseng. Unlike the ginsenosides of the Panax genus, however, the eleutherosides are a chemically diverse group of plant chemicals (Iignans, sterols, phenylpropanoids, coumarins, and others), and are not unique to E. senticosus.Soviet researchers conducted numerous animal experiments with Siberian ginseng, and reported enhanced physical en?durance and resistance to infection, radiation, cancer, toxins, and iI variety of environmental extremes. Anabolic, estrogenic, an?liviral, hypotensive, and many other effects have also been demonstrated in animal models. Conflicting reports in which extracts induced both hypoglycemia and hyperglycemia in animals, or enhanced both CNS sedation and stimulation, have been explained by the “adaptogenic” properties of the herb. Alternatively, it may also be explained by different extracts or experimental conditions. Most of the earlier animal endurance studies were unblinded, which also raises the question of investigator bias; a more recent blinded study was negative.

Limited pharmacologic data is available in humans. In a report?edly double-blind, placebo-controlled study, 10 ml t.i.d. of a German product for 4 weeks significantly increased lymphocytes by about 50% in 36 healthy volunteers. In an unblinded, randomized, con?trolled study, 25 drops t.i.d. of an ethanolic root extract decreased glucose and cholesterol (total, LOL, and triglycerides), and increased neutrophil and lymphocyte activity in 50 healthy volunteers.

Clinical Trials:

Most of the original Russian clinical studies have been reviewed and summarized. Initial research reported that athletes performed better; sportsmen had better endurance and concentration; and workers had fewer sick days when taking Siberian ginseng. In multiple studies that included over 2100 healthy subjects, Siberian ginseng was reported to demonstrate adaptogenic effects to help subjects withstand various adverse conditions and stressors (work load, noise, motion, heat, etc.), resulting in enhanced work performance. Studies in over 2200 unhealthy patients reported “benefits” in various diseases such as atherosclerosis and heart disease, acute pyelonephritis, diabetes, chronic bronchitis, hypertension and hypotension, trauma, neuroses, and cancer. However, outcome measures and actual clini?cal benefits are not well defined. Moreover, these studies were uncontrolled or unblinded, and would not meet today’s standards for high-quality clinical research.

In more recent controlled trials, benefits for athletic endurance were initially reported in a single-blind, placebo-controlled study, and improvements in muscle strength demonstrated in a placebocontrolled trial with unclear blinding. A Chinese study also reported an increased anaerobic threshold of power load emd decreased respiratory quotient (suggesting enhanced fat metabo” lism during exercise). However, more rigorous double-blind studies have failed to verify these potential beneficial effects. A series of small controlled trials using treadmill or cycle ergometry found no ergonomic benefits for a brand of Siberian ginseng called Endurox. Another well-designed trial of 20 runners found no ergonomic benefits with an ethanolic extract of eleutherosides Band E given daily for 6 weeks compared to placebo. A well-designed, double-blind, crossover study found no measurable ergonomic or metabolic benefits in nine cyclists, randomly given placebo or 1200 mg Siberian ginseng daily for 7 days before two separate endurance cycling trials.

Adverse Effects:

Siberian ginseng is considered safe and nontoxic, although data is limited. No side effects were reported in any of the recent human trials, and there are no well-documented case reports of adverse effects. In the original Russian studies, adverse events were not reported in otherwise healthy subjects, although it was suggested that Siberian ginseng should not be used when blood pressures exceed 180/90. In “unhealthy” patients, insomnia, arrhythmias, hypertension, headaches, irritability, and anxiety reactions were occasionally reported. Caution is thus advised for patients with cardiac disease, hypertension, psychiatric diseases, or when using caffeine or other stimulants, although these potential side effects are not well established.

Side Effects and Interactions:

In two separate case reports, adulterated or mislabeled eleutherococcus preparations (most likely with Periploca sepium, which contains cardioactive glycosides) were associated with androgenization in a newborn and with an increased digoxin level absent toxicity. Safety of Siberian ginseng is unknown in women who are pregnant or breast feeding.

Preparations & Doses:

Multiple products are on the U.S. market, from dried herb preparations to a variety of extracts. In the original Russian studies, doses were usually taken for up to 4-8 weeks at a time, interrupted by 2-to 3-week ginseng-free in?tervals; however, there is no data to support these regimens. Common doses of encapsulated extracts currently on the market include one to three 100-400 mg capsules given 2-3 times daily, roughly equivalent to 1-4 g/day or more of a dried root product.

Summary Evaluation:

Siberian ginseng is commonly used as an adaptogen to help modulate responses to stressors and to enhance mental and physical stamina and endurance. These claims are primarily based on animal studies and early clinical investigations by Soviet researchers. Siberian ginseng does not enhance physical endurance based on more recent, well-designed clinical trials. Limited studies suggest that Siberian ginseng may enhance WBC activity, reduce cholesterol and glucose, enhance memory, and benefit patients with herpes simplex infections, but these studies require confirmation and, in general, the efficacy of Siberian gin?seng is not established beyond a reasonable doubt for any indica?tion. Based on limited data, Siberian ginseng appears safe, with no well-documented adverse effects.



Thanks to Steve Mathew for contributing this article to our Ginseng blog:

Steve Mathew is a writer, who writes many great articles on herbal medicines for common ailments and diseases. For more information on herbal remedies and home remedies visit our site on health care.



Wisconsin American Ginseng

Boost Your Energy Levels With Panax Ginseng

March 8, 2009 by Ginseng Reviews and Tips  
Filed under About Ginseng

Panax is a type of perennial plant with fleshy roots, and grows in Eastern Asia. Ginsengs contain ginsenosides that are triterpene saponins, steroidal compounds that are found only in Panax ginseng. The effects of these saponins are difficult to establish, but they are believed to be behind the properties of ginseng.

Panax ginseng is found predominantly in Korea, China and Siberia, although a genus has also been found in Vietnam. Panax are adaptogenic herbs that help promote resistance to anxiety, fatigue and stress, and are said to adapt the body to resist a number of different stressors. It has been proposed that adaptogenic herbs can balance the endocrine hormones of the hypothalamus, pituitary and adrenal axis.

They also normalize the immune system, and increase the activity of phagocytes, the killer cells. Additionally, they not only help to maintain homeostasis, but are believed to go further and act as allostatic agents, adapting response to maintain system stability in a more dynamic fashion, by changing interactive functions as opposed to the individual adaption’s made in homeostasis.

Not all ginsengs are the same, and although Siberian ginseng is an adaptogen, it is not a true ginseng. Its roots are woody rather than fleshy, and it contains eleutherosides as opposed to ginsenosides. These also are triterpenoid saponins, but of a different adaptogen. The herb is actually Eleutherococcus senticosus as opposed to Panax ginseng and P. quinquefolius, both true ginsengs. Siberian ginseng was misnamed as a marketing ploy.

American ginseng is Panax quinquefolius, sometimes referred to by the Chinese as Huaqishen. It, too, is an adaptogen and a true ginseng, containing ginsenosides. However, it contains much less ginsenonide Rg1 than panax. This ginsenonide appears to possess estrogen-like activity and improves spatial learning. The other forms of ginesonide found in panax ginseng are:

Ginsenoside Rb1: This appears in greatest concentration in American ginseng, and appears to have an effect on the reproductive system. It not only has an effect on the testicles, but is believed to increase testosterone production through its stimulating effect on luteinizing hormone. It also helps to rdeduce the incidence of angiogenesis, which is the formation of new blood vessels from old, and also a stage in the development of malignant tumors from dormant ones.

Ginsenoside Rc: this possesses sedative properties, and in a study on breast cancer was found to have an effect in inhibiting the growth of these particular cancer cells. Ginsenoside Rc might therefore have use in the treatment or prevention of breast cancer. Studies have also suggested that this ginsenoside could increase the motility of sperm: the motiliy of sperm was found to increase significantly in a solution of ginsenoside Rc.

Ginsenoside Rf: this is present only in panax ginseng, and studies have indicate that it has an inhibitory effect on the Ca2+ neural channels in the brain, and so cokld have an analgesic effect. Studies have as yet failed to explain this effect that is seen in animal tests, but are continuing on this ginsenoside.

Ginsenoside Re: this ginsenoside has strong antioxidant effects and has a significant antidiabetic effect in that is reduces insulin resistance, which is likely why ginseng is taken to treat Type 2 diabetes. Studies are ongoing into the properties of this ginsenoside, and also on the other 10 or more that are known to be present in Panax ginseng. The effects of ginseng are difficult to establish with certainity because they work through so many different pathways and it is difficult to isolate one. More than one ginsenoside, for example, affects the calcium channels in the brain, and it is difficult to determine which does what.

There are fewer ginsenosides in Panax quinquefoilius, and in the USA it is only the panax version that can be traded as simply ‘ginseng’. One of the main problems with all ginsengs is that although it is one of the most studied plants, the majority of the studies have been on animals, and due to this, and the difficulties caused by the multiple pathways described earlier, many of the postulations have not been proved in humans.

However, if the theory as it is know today is taken into consideration along with the traditional uses of ginseng in traditional Indian (ayurvedic), Chinese and Native American medicine, it would be fairly accurate to say that ginseng is useful in helping your body to recover after illness or surgery, and to help you to deal with stress. It has also been proved to lower your blood glucose (sugar) levels, and help in the treatment of Type II diabetes, as already mentioned. There is evidence that it helps to boost your mental performance, memory and might help to slow down the onset of Alzheimer’s disease.

Ginseng can also give a boost to your energy levels, and it is genarally accepted that panax ginseng is more effective than the American version. In traditional medicine, Asian ginseng is said to be warming, and the American variery cooling. Thus Panax ginseng is useful for people recovering from illness and trying to recover their strength, acts as a tonic, stimulant and supports the immune system. In other words it helps the body to get whole again after being depleted.

It should not be used if you get very hot and red, such as with heat stroke, unless you use it in combination with the American version, because these are conditions of high yang and this type of ginseng will increase the yang even further.

American ginseng, on the other hand, is good for those with fevers, hypertension (high blood pressure), and suffereing the effcts of heat. It helps build the yin and reduce the yang, so if you always feel flushed and hot or are hyperactive then go for the American, and if you easily get chilled or find your hands and feet get cold very easily, reach for the Asian ginseng to increase your yang.

You often find ginseng as an ingredient in soft drinks, but the concentration is so low that it has no metabolic or pharmacological effect. The dose to be taken should be as stated on the pack, since there is no specific standardization. It has been noted that the effects can be lost if an excess of ginseng is taken, but generally the herb is safe and if you feel a bit down or lacking in energy, ginseng can work wonders for you.



Thanks to Darrell Miller for contributing this article to our Ginseng blog:
More information on panax ginseng is available at VitaNet ®, LLC Health Food Store. http://vitanetonline.com/



Chinese Traditional Herbs